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Linked databases
AetherXeno is built on and cross-links to established community resources. Each card states exactly how AetherXeno uses the resource, so every external claim is traceable to its source.
Pharmacogenomics and drugs
Curated pharmacogenomic knowledge and clinical variant annotations.
AetherXeno uses it for: Source of the CAMIP affected substrate drugs, mapped from clinical annotations.
License: CC-BY-SA 4.0
Clinical Pharmacogenetics Implementation Consortium gene and drug guidelines.
AetherXeno uses it for: Reference for the pharmacist reviewed drug guidance, for example UGT1A1 and CYP2C19.
License: CC-BY-SA 4.0
Pharmacogene variation and star allele nomenclature.
AetherXeno uses it for: Canonical pharmacogene and allele reference for the panel genes.
License: Free academic use
Drug, target and metabolism reference.
AetherXeno uses it for: Cross check of substrate and inducer relationships.
License: Academic, non-commercial
Variants and clinical significance
Clinical interpretations of sequence variation.
AetherXeno uses it for: Per variant ClinVar cross annotation, 28,227 variants; each links back to its ClinVar record.
License: Public domain (NCBI)
Reference SNP identifiers and rsIDs.
AetherXeno uses it for: rsID identity for stored variants and search; each links back to dbSNP.
License: Public domain (NCBI)
Population allele frequencies.
AetherXeno uses it for: Allele frequency on the observed variant layer; each links back to the gnomAD browser.
License: Free, no restrictions
Curated genome wide association study results.
AetherXeno uses it for: Trait cross annotation, 856 allele-matched associations; each links back to the GWAS Catalog.
License: EMBL-EBI terms, open
Genome, regulation and expression
Genome annotation and a public REST API.
AetherXeno uses it for: Real time rsID to GRCh38 coordinate resolution.
License: Open, no restrictions
Reference genome, gene models and tracks.
AetherXeno uses it for: refGene gene models for the locus and nearest gene logic.
License: Free, academic / non-profit
Transcription factor binding profiles.
AetherXeno uses it for: FIMO motif scan for RXRA, NR1I2, NR1H4, AhR and HNF4A; each motif links back to its JASPAR matrix.
License: Open access
Tissue specific expression quantitative trait loci.
AetherXeno uses it for: Liver eQTL cross annotation and an independent enrichment check; each eGene links back to GTEx.
License: Summary stats open access
Candidate cis regulatory elements across cell types.
AetherXeno uses it for: cCRE context for the region confidence layer.
License: Open, no restrictions
AetherXeno does not rehost these databases. It links back to every source record, and where it redistributes derived annotations (the joined cross-annotation tables in the Evidence downloads and the Zenodo archive) it does so under each source's terms, with attribution. Exact terms are governed by each resource. See the Documentation for data availability and how each layer is built.